Life Sciences

University of Queensland
Life Sciences
Pascale Wehr

Rheumatoid arthritis (RA) is an autoimmune disease where humoral and cellular immunities against multiple self-antigens are implicated in pathogenesis. Autoantigen-specific CD4+ T cells have been detected in RA patients, and a biased T cell...

Ryerson University
Life Sciences
Morla Phan

 

Breast cancer detection through mammography has several drawbacks resulting in false positives and false negatives. Biomarkers are proteins in blood that have the potential to diagnose breast cancer with more objective accuracy....

University of Dundee
Life Sciences
David Wright

The purpose of this project was to study the druggability of an epigenetic reader domain, the PHD (Plant homeodomain) zinc finger. Modulating the interaction between histones and reader domains using small molecule probes has been of great...

Trinity College, University of Dublin
Life Sciences
Robert White

The transcription factor RORa is a nuclear receptor which belongs to the retinoic acid-related orphan receptor (ROR) family of receptors. RORa is highly conserved throughout many species and has many known functions in the body including cell...

Nanyang Technological University
Life Sciences
Soon Keong Wee

The recent emergence of antibiotic-resistant bacteria globally is threatening to make common infections untreatable. One such superbug is methicillin-resistant Staphylococcus aureus (MRSA), a bacterial species capable of causing skin and soft...

Monash University
Life Sciences
James Virth

Background & Purpose: Ischaemic stroke is a leading cause of death and disability globally. Despite its impact, there remains a paucity of clinically efficacious treatments. Expression and activity of the NADPH oxidases is upregulated in the...

University College London
Life Sciences
Tin Yan Emily Tong

My research focus is on two hallmarks of cancer concerned with mitochondria
deregulation of cellular energetics and resistance to apoptosis. The Warburg Effect
states that cancer cells with oxidative phosphorylation (OXPHOS)...

Queen's University Belfast
Life Sciences
Nicole Todd

Grey seals (Halichoerus grypus) are capital breeders, relying on stored energy reserves for the duration of the breeding season. Disturbance events are known to elicit high energy behaviours which can have a negative effect on the fitness of...

University of Toronto
Life Sciences
Natasha Tang

A fundamental question in human genetics is how mutation leads to disease. Specifically, different mutations within a single gene may be associated with a wide range of disease phenotypes. According to the edgotype model of disease, this...

University of Cambridge
Life Sciences
Katy Surman

Individuals with highly impulsive traits are known to be more vulnerable to developing compulsive behaviours, which in humans include Obsessive Compulsive Disorder and compulsive drug use. Whilst the exact mechanisms behind this transition are...